Article
The role of renin-angiotensin-aldosterone system genes in the progression of chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2015
Kelly Tanika N, Raj Dominic, Rahman Mahboob, Kretzler Matthias, Kallem Radhakrishna R, Ricardo Ana C, Rosas Sylvia E, Tao Kaixiang, Xie Dawei, Hamm Lotuce Lee, He Jiang
Abstract excerpt
BACKGROUND: We conducted single-marker, gene- and pathway-based analyses to examine the association between renin-angiotensin-aldosterone system (RAAS) variants and chronic kidney disease (CKD) progression among Chronic Renal Insufficiency Cohort study participants. METHODS: A total of 1523 white and 1490 black subjects were genotyped for 490 single nucleotide polymorphisms (SNPs) in 12 RAAS genes as part of the...
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