Article
Sox4 participates in the modulation of Schwann cell myelination.
The European journal of neuroscience - 1 Jul 2015
Bartesaghi Luca, Arnaud Gouttenoire Estelle, Prunotto Andrea, Médard Jean-Jacques, Bergmann Sven, Chrast Roman
Abstract excerpt
In order to identify new regulators of Schwann cell myelination potentially playing a role in peripheral nervous system (PNS) pathologies, we analysed gene expression profiling data from three mouse models of demyelinating neuropathies and from the developing PNS. This analysis revealed that Sox4, which encodes a member of the Sry-related high-mobility group box protein family, was consistently upregulated in all...
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