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Article

Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells.

Journal of neurochemistry - 1 Feb 2010

Reiprich Simone, Kriesch Jana, Schreiner Silke, Wegner Michael

Abstract excerpt

The high-mobility group domain transcription factor Sox10 is believed to influence myelination in Schwann cells by directly activating myelin genes and by inducing Krox20 as a pivotal regulator of peripheral myelination. Krox20 induction at this stage is thought to be mediated by the myelinating Schwann cell element 35 kb downstream of the Krox20 transcriptional start site and requires cooperation with Oct6....

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Source

Identifiers

PMID: 19922439
DOI: 10.1111/j.1471-4159.2009.06498.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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