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Article

Functional polymorphisms of ITGB1 are associated with clinical outcome of Chinese patients with resected colorectal cancer.

Cancer chemotherapy and pharmacology - 1 Jun 2015

Zhou Feng, Huang Xiaojun, Zhang Zhaohui, Chen Yibing, Liu Xiaonan, Xing Jinliang, He Xianli

Abstract excerpt

PURPOSE: Integrin β1 (ITGB1) has been recognized to play a major role in tumor growth, invasion and metastasis. However, effects of single-nucleotide polymorphisms (SNPs) in ITGB1 gene on the prognosis of patients with colorectal cancer (CRC) have not been reported. METHODS: A total of 372 patients with resected colorectal adenocarcinoma were enrolled in our study. Three functional SNPs (rs2230395, rs1187075 and...

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Source

Identifiers

PMID: 25894721
DOI: 10.1007/s00280-015-2745-4

Genes

ITGB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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