Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potentially functional genetic variants in KDR gene as prognostic markers in patients with resected colorectal cancer.

Cancer science - 1 Mar 2012

Dong Guanglong, Guo Xu, Fu Xiaoying, Wan Shaogui, Zhou Feng, Myers Ronald E, Bao Guoqiang, Burkart Ashlie, Yang Hushan, Xing Jinliang

Abstract excerpt

Angiogenesis plays a key role in the development and treatment response of various tumors. The signaling transductions mediated by the binding of vascular endothelial growth factor (VEGF) to its receptor KDR (kinase insert domain receptor) is the most important pathway in tumor angiogenesis. Single nucleotide polymorphisms (SNPs) in VEGF have been extensively implicated in the etiology and treatment outcome of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Combined Chemotherapy Protocols
Share to Asian People

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chemotherapy, Adjuvant

Share to Colorectal Neoplasms

Share to Kaplan-Meier Estimate

Share to Neoplasm Recurrence, Local

Share to Promoter Regions, Genetic

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Open in PubMed Open full text

Identifiers

PMID: 22182247
DOI: 10.1111/j.1349-7006.2011.02194.x
PMCID: PMC7713614

Genes

KDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potentially functional genetic variants in KDR gene as prognostic markers in patients with resected colorectal cancer.PMID 22182247Read ↗

Genetic variants in the KDR gene is associated with the prognosis of transarterial chemoembolization treated hepatocellular carcinoma.Semantic proximity Read ↗

Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer.Semantic proximity Read ↗

The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors.Semantic proximity Read ↗

Genetic Variants of VEGF (rs201963 and rs3025039) and KDR (rs7667298, rs2305948, and rs1870377) Are Associated with Glioma Risk in a Han Chinese Population: a Case-Control Study.Semantic proximity Read ↗

Prognostic significance of vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer.Semantic proximity Read ↗

[The impact of genetic variation of KDR on clinical outcomes of advanced colorectal cancer patients treated by first line bevacizumab based regimens].Semantic proximity Read ↗

Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection.Semantic proximity Read ↗

Impact of Angiogenesis- and Hypoxia-Associated Polymorphisms on Tumor Recurrence in Patients with Hepatocellular Carcinoma Undergoing Surgical ResectionSemantic proximity Read ↗

A common and functional gene variant in the vascular endothelial growth factor a predicts clinical outcome in early-stage breast cancer.Semantic proximity Read ↗

GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis.Semantic proximity Read ↗

The association of VEGF rs833061 and rs2010963 polymorphisms with susceptibility to colorectal cancer in an Iranian population.Semantic proximity Read ↗

The Influence of KDR Genetic Variation on the Efficacy and Safety of Patients With Advanced NSCLC Receiving First-Line Bevacizumab Plus Chemotherapy Regimen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.