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Influence of TS and ABCB1 gene polymorphisms on survival outcomes of 5‑FU-based chemotherapy in a Chinese population of advanced gastric cancer patients.

Wiener klinische Wochenschrift - 1 Jun 2017

Chen Jun, Ying Xueming, Zhang Ling, Xiang Xiaojun, Xiong Jianping

Abstract excerpt

To investigate the impacts of gene variations on survival outcomes of advanced gastric cancer (AGC) patients treated with 5‑fluorouracil (5-FU)-based chemotherapy, we analyzed the associations of 2 indels of the TS gene rs34743033 (double or triple tandem repeats of a 28 bp sequence in 5'-UTR, denoted as 2R or 3R allele) and rs16430 (a 6 bp variation at 1494 bp in 3'-UTR, denoted as ins6 or del6 allele) and 2...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Identifiers

PMID: 28074308
DOI: 10.1007/s00508-016-1147-x

Genes

ABCB1

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