Article

micronuclAI: Automated quantification of micronuclei for assessment of chromosomal instability

2024-05-29

Abstract excerpt

Chromosomal instability (CIN) is a hallmark of cancer that drives metastasis, immune evasion and treatment resistance. CIN results from chromosome mis-segregation events during anaphase, as excessive chromatin is packaged in micronuclei (MN), that can be enumerated to quantify CIN. Despite recent advancements in automation through computer vision and machine learning, the assessment of CIN remains a predominantly...

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Literature Corpus work: 18cc9ae8-3446-556e-b43e-968d55bc5edb
DOI: 10.1101/2024.05.24.595722

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