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Article

The single nucleotide polymorphism Gly482Ser in the PGC-1α gene impairs exercise-induced slow-twitch muscle fibre transformation in humans.

PloS one - 1 Jan 2015

Steinbacher Peter, Feichtinger René G, Kedenko Lyudmyla, Kedenko Igor, Reinhardt Sandra, Schönauer Anna-Lena, Leitner Isabella, Sänger Alexandra M, Stoiber Walter, Kofler Barbara, Förster Holger, Paulweber Bernhard, Ring-Dimitriou Susanne

Abstract excerpt

PGC-1α (peroxisome proliferator-activated receptor γ co-activator 1α) is an important regulator of mitochondrial biogenesis and a master regulator of enzymes involved in oxidative phosphorylation. Recent evidence demonstrated that the Gly482Ser single nucleotide polymorphism (SNP) in the PGC-1α g...

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Source

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Identifiers

PMID: 25886402
DOI: 10.1371/journal.pone.0123881
PMCID: PMC4401702

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25886402-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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