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Article

Kernel Approach for Modeling Interaction Effects in Genetic Association Studies of Complex Quantitative Traits.

Genetic epidemiology - 1 Jul 2015

Broadaway K Alaine, Duncan Richard, Conneely Karen N, Almli Lynn M, Bradley Bekh, Ressler Kerry J, Epstein Michael P

Abstract excerpt

The etiology of complex traits likely involves the effects of genetic and environmental factors, along with complicated interaction effects between them. Consequently, there has been interest in applying genetic association tests of complex traits that account for potential modification of the genetic effect in the presence of an environmental factor. One can perform such an analysis using a joint test of gene...

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Identifiers

PMID: 25885490
DOI: 10.1002/gepi.21901
PMCID: PMC4469530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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