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Article

Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls.

BMC cancer - 31 Mar 2015

Kelley Robin K, Magbanua Mark Jesus M, Butler Timothy M, Collisson Eric A, Hwang Jimmy, Sidiropoulos Nikoletta, Evason Kimberley, McWhirter Ryan M, Hameed Bilal, Wayne Elizabeth M, Yao Francis Y, Venook Alan P, Park John W

Abstract excerpt

BACKGROUND: Circulating biomarkers are urgently needed in hepatocellular carcinoma (HCC). The aims of this study were to determine the feasibility of detecting and isolating circulating tumor cells (CTCs) in HCC patients using enrichment for epithelial cell adhesion molecule (EpCAM) expression, to examine their prognostic value, and to explore CTC-based DNA sequencing in metastatic HCC patients compared to a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25884197
DOI: 10.1186/s12885-015-1195-z
PMCID: PMC4399150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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