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Progress and challenges of sequencing and analyzing circulating tumor cells

22 Nov 2017

Abstract excerpt

Circulating tumor cells (CTCs) slough off primary tumor tissues and are swept away by the circulatory system. These CTCs can remain in circulation or colonize new sites, forming metastatic clones in distant organs. Recently, CTC analyses have been successfully used as effective clinical tools to monitor tumor progression and prognosis. With advances in next-generation sequencing (NGS) and single-cell sequencing...

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PMID: 29168077
DOI: 10.1007/s10565-017-9418-5

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