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High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma

26 Jul 2018

Abstract excerpt

Patients with hepatocellular carcinoma (HCC) release tumor cells to the bloodstream, which can be detected using cell surface markers. Despite numerous reports suggest a direct correlation between the number of circulating tumor cells (CTCs) and poor clinical outcomes, few studies have provided a thorough molecular characterization of CTCs. Due to the limited access to tissue samples in patients at advanced...

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PMID: 30068984
DOI: 10.1038/s41598-018-30047-y

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