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Article

Applications of molecular barcode sequencing for the detection of low-frequency variants in circulating tumour DNA from hepatocellular carcinoma.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2022

Lee Hye Won, Kim Esl, Cho Kyung Joo, Park Hye Jung, Seo Jieun, Lee Hyeonah, Baek Eunha, Choi Jong Rak, Han Kwang-Hyub, Lee Seung-Tae, Park Jun Yong

Abstract excerpt

PURPOSE: Liquid biopsy has emerged as a promising tool for minimally invasive and accurate detection of various malignancies. We aimed to apply molecular barcode sequencing to circulating tumour DNA (ctDNA) from liquid biopsies of hepatocellular carcinoma (HCC). STUDY DESIGN: Patients with HCC or benign liver disease were enrolled between 2017 and 2018. Matched tissue and serum samples were obtained from these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35776657
DOI: 10.1111/liv.15356

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