Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Digital detection of multiple minority mutants and expression levels of multiple colorectal cancer-related genes using digital-PCR coupled with bead-array.

PloS one - 1 Jan 2015

Huang Huan, Li Shuo, Sun Lizhou, Zhou Guohua

Abstract excerpt

To simultaneously analyze mutations and expression levels of multiple genes on one detection platform, we proposed a method termed "multiplex ligation-dependent probe amplification-digital amplification coupled with hydrogel bead-array" (MLPA-DABA) and applied it to diagnose colorectal cancer (CR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Cyclooxygenase 2
Share to Genes, myc

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, ras

Share to Hyaluronan Receptors

Share to Multiplex Polymerase Chain Reaction

Share to Mutation Rate

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 25880764
DOI: 10.1371/journal.pone.0123420
PMCID: PMC4399940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25880764-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Digital detection of multiple minority mutants and expression levels of multiple colorectal cancer-related genes using digital-PCR coupled with bead-array.PMID 25880764Read ↗

Digital detection of multiple minority mutants in stool DNA for noninvasive colorectal cancer diagnosis.Semantic proximity Read ↗

Highly sensitive mutation detection based on digital amplification coupled with hydrogel bead-array.Semantic proximity Read ↗

Rapid and multi-target genotyping of Helicobacter pylori with digital microfluidics.Semantic proximity Read ↗

Mutation detection in K-ras, BRCA1, BRCA2, and p53 using PCR/LDR and a universal DNA microarray.Semantic proximity Read ↗

Detection of single-base mutations using 1-D microfluidic beads array.Semantic proximity Read ↗

A low-cost hydrogel chip for SNP typing by the incorporation of Cy5-dCTP into label-free allele-specific probes hybridizing to gel-immobilized targets.Semantic proximity Read ↗

A hydrogel beads based platform for single-cell phenotypic analysis and digital molecular detectionSemantic proximity Read ↗

Visual detection of DNA mutation using multicolor fluorescent coding.Semantic proximity Read ↗

Development of a ligase detection reaction/CGE method using a LIF dual-channel detection system for direct identification of allelic composition of mutated DNA in a mixed population of excess wild-type DNA.Semantic proximity Read ↗

Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations.Semantic proximity Read ↗

Digital Polymerase Chain Reaction Assay for the Genetic Variation in a Sporadic Familial Adenomatous Polyposis Patient Using the Chip-in-a-tube Format.Semantic proximity Read ↗

Universal DNA microarray method for multiplex detection of low abundance point mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.