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Article

Tissue factor pathway inhibitor polymorphisms in women with and without a history of venous thrombosis and the effects of postmenopausal hormone therapy.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2010

Opstad Trine B, Eilertsen Anette L, Høibraaten Else, Skretting Grethe, Sandset Per Morten

Abstract excerpt

Postmenopausal hormone therapy is associated with marked reduction in tissue factor pathway inhibitor (TFPI) levels, and low TFPI levels have been associated with increased risk of venous thrombosis. Polymorphisms in the TFPI gene may affect the expression of TFPI. We aimed to investigate the influences of such polymorphisms on plasma TFPI levels and to investigate the effect of hormone therapy. Four single...

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Source

Identifiers

PMID: 20453636
DOI: 10.1097/MBC.0b013e32833a06cd

Genes

TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Tissue factor pathway inhibitor polymorphisms in women with and without a history of venous thrombosis and the effects of postmenopausal hormone therapy.PMID 20453636Read ↗

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The 536C→T Transition in the Human Tissue Factor Pathway Inhibitor (TFPI) Gene Is Statistically Associated with a Higher Risk for Venous ThrombosisSemantic proximity Read ↗

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