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Article

Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia.

The American journal of psychiatry - 1 Jul 2018

Kauppi Karolina, Rosenthal Sara Brin, Lo Min-Tzu, Sanyal Nilotpal, Jiang Mian, Abagyan Ruben, McEvoy Linda K, Andreassen Ole A, Chen Chi-Hua

Abstract excerpt

OBJECTIVE: Antipsychotic drugs were incidentally discovered in the 1950s, but their mechanisms of action are still not understood. Better understanding of schizophrenia pathogenesis could shed light on actions of current drugs and reveal novel "druggable" pathways for unmet therapeutic needs. Recent genome-wide association studies offer unprecedented opportunities to characterize disease gene networks and uncover...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29495895
DOI: 10.1176/appi.ajp.2017.17040410
PMCID: PMC6028303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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