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Transcriptome analysis of controlled and therapy-resistant childhood asthma reveals distinct gene expression profiles

11 Apr 2015

Abstract excerpt

BACKGROUND: Children with problematic severe asthma have poor disease control despite high doses of inhaled corticosteroids and additional therapy, leading to personal suffering, early deterioration of lung function, and significant consumption of health care resources. If no exacerbating factors, such as smoking or allergies, are found after extensive investigation, these children are given a diagnosis of...

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PMID: 25863981
DOI: 10.1016/j.jaci.2015.02.026

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