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Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

6 Dec 2012

Abstract excerpt

The causes of severe childhood asthma are poorly understood. Our aim was to define global patterns of gene expression in children with severe therapy-resistant and controlled asthma. White blood cells were isolated and the global transcriptome profile was characterised using the Affymetrix Human Gene ST 1.0 chip in children with severe, therapy-resistant asthma (n=17), controlled asthma (n=19) and healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23222870
DOI: 10.1183/09031936.00077712

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