Article
PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling.
BMC bioinformatics - 1 Jan 2015
Park Danny S, Baran Yael, Hormozdiari Farhad, Eng Celeste, Torgerson Dara G, Burchard Esteban G, Zaitlen Noah
Abstract excerpt
Identifying segments in the genome of different individuals that are identical-by-descent (IBD) is a fundamental element of genetics. IBD data is used for numerous applications including demographic inference, heritability estimation, and mapping disease loci. Simultaneous detection of IBD over multiple haplotypes has proven to be computationally difficult. To overcome this, many state of the art methods estimate...
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