Article
[Detection and clinical significance of JAK2 mutation in 412 patients with chronic myeloproliferative neoplasms].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 2009
Chao Hong-Ying, Fan Zheng, Zhang Ri, Shen Yi-Min, Chen Wan, Fei Hai-Rong, Zhu Zi-Ling, Feng Yu-Feng, Chen Zi-Xing, Xue Yong-Quan
Abstract excerpt
OBJECTIVE: To investigate the frequency of JAK2V617F mutation in Chinese patients with chronic myeloproliferative neoplasms (MPN) and to study the relationship between JAK2V617F mutation and clinical characteristics. METHODS: JAK2V617F mutation was screened by allele-specific polymerase chain reaction (AS-PCR). RESULTS: JAK2V617F mutation was detected in 277 of the 412 patients with MPN. The frequency of...
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