Article
[A novel quantitative JAK2V617F detection kit: prospective clinical performance study comparing MPN patients and healthy subjects].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2000
Kirito Keita, Koike Michiaki, Noguchi Masaaki, Kizaki Masahiro, Katayama Naoyuki, Sugimoto Yuka, Dobashi Nobuaki, Usui Noriko, Komatsu Norio
Abstract excerpt
The JAK2V617F mutation is the commonest major genetic mutation of myeloproliferative neoplasms (MPNs) and has been defined in the WHO diagnostic criteria for MPNs. However, there is still no approved in vitro diagnostic test kit available in Japan. We evaluated a JAK2V617F allele quantification kit (test method) in a prospective, multicenter clinical performance study involving patients with MPNs who were...
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