Article
[Clinical study on relationship between JAK2 V617F mutation and chronic myeloproliferative disorders].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Feb 2008
Zhang Yue, Li Lin, Nie Ling, Yu Yang, Yang Yi-Hong, Zhang Zhan-Qiang, Yang Lin, Xu Shi-Cai, Xiao Zhi-Jian
Abstract excerpt
OBJECTIVE: To investigate JAK2V617F mutation and its clinical significance in patients with chronic myeloproliferative disorders (cMPD). METHODS: A retrospective study was performed on 523 cMPD patients diagnosed according to the current World Health Organization (WHO) criteria. Allele-specific PCR (ASP) was used to identify JAK2V617F mutation, the mutation status was analyzed by PCR-RFLP, and the results were...
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