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Article

Whole exome sequencing identifies driver mutations in asymptomatic computed tomography-detected lung cancers with normal karyotype.

Cancer genetics - 1 Apr 2015

Belloni Elena, Veronesi Giulia, Rotta Luca, Volorio Sara, Sardella Domenico, Bernard Loris, Pece Salvatore, Di Fiore Pier Paolo, Fumagalli Caterina, Barberis Massimo, Spaggiari Lorenzo, Pelicci Pier Giuseppe, Riva Laura

Abstract excerpt

The efficacy of curative surgery for lung cancer could be largely improved by non-invasive screening programs, which can detect the disease at early stages. We previously showed that 18% of screening-identified lung cancers demonstrate a normal karyotype and, following high-density genome scannin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25850996
DOI: 10.1016/j.cancergen.2015.02.004

Genes

KEAP1
MSH3
PMS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25850996-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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