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Exome sequencing identifies somatic mutations in novel driver genes in non-small cell lung cancer.

Aging - 6 Jul 2020

Zhang Manman, Zhang Lele, Li Yan, Sun Feng, Fang Ya, Zhang Ruijia, Wu Jin, Zhou Guanbiao, Song Huaidong, Xue Liqiong, Han Bing, Zheng Cuixia

Abstract excerpt

Lung cancer is the leading cause of cancer death worldwide and accounts for more than one-third of all newly diagnosed cancer cases in China. Therefore, it is of great clinical significance to explore new driver gene mutations in non-small-cell lung cancer (NSCLC). Using an initial bioinformatic analysis, we identified somatic gene mutations in 13 patients with NSCLC and confirmed these mutations by targeted...

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Identifiers

PMID: 32629428
DOI: 10.18632/aging.103500
PMCID: PMC7377869

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