Article
Genomic characterization of asymptomatic CT-detected lung cancers.
Oncogene - 3 Mar 2011
Belloni E, Veronesi G, Micucci C, Javan S, Minardi S P, Venturini E, Maisonneuve P, Volorio S, Riboni M, Bellomi M, Scanagatta P, Taliento G, Pelosi G, Pece S, Spaggiari L, Pelicci P G
Abstract excerpt
Computed tomography (CT) screening of lung cancer allows the detection of early tumors. The objective of our study was to verify whether initial asymptomatic lung cancers, identified by high-resolution low-dose CT (LD-CT) on a high-risk population, show genetic abnormalities that could be indicative of the early events of lung carcinogenesis. We analyzed 78 tumor samples: 21 (pilot population) from heavy smokers...
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