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Article

Aberrant palmitoylation in Huntington disease

1 Apr 2015

Abstract excerpt

Huntington disease (HD) is an adult-onset neurodegenerative disease caused by a CAG expansion in the HTT gene. HD is characterized by striatal atrophy and is associated with motor, cognitive and psychiatric deficits. In the presence of the HD mutation, the interactions between huntingtin (HTT) and huntingtin interacting protein 14 (HIP14 or DHHC17) and HIP14-like (DHHC13, a HIP14 orthologue), palmitoyl...

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PMID: 25849918
DOI: 10.1042/bst20140242

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Aberrant palmitoylation in Huntington diseasePMID 25849918Read ↗

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