Article
Identification of binding sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L.
PloS one - 1 Jan 2014
Sanders Shaun S, Mui Katherine K N, Sutton Liza M, Hayden Michael R
Abstract excerpt
Huntington disease is an adult onset neurodegenerative disease characterized by motor, cognitive, and psychiatric dysfunction, caused by a CAG expansion in the HTT gene. Huntingtin Interacting Protein 14 (HIP14) and Huntingtin Interacting Protein 14-like (HIP14L) are palmitoyl acyltransferases (PATs), enzymes that mediate the post-translational addition of long chain fatty acids to proteins in a process called...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
