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Article

Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus.

Journal of translational medicine - 1 Mar 2015

Ascierto Maria Libera, Bozzano Federica, Bedognetti Davide, Marras Francesco, Schechterly Cathy, Matsuura Kentaro, Picciotto Antonino, Marenco Simona, Zhao Yingdong, DeGiorgi Valeria, Sommariva Michele, Moretta Lorenzo, Wang Ena, Alter Harvey J, Marincola Francesco M, De Maria Andrea

Abstract excerpt

BACKGROUND: Differences in the expression of Natural Killer cell receptors have been reported to reflect divergent clinical courses in patients with chronic infections or tumors. However, extensive molecular characterization at the transcriptional level to support this view is lacking. The aim of this work was to characterize baseline differences in purified NK cell transcriptional activity stratified by response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25849716
DOI: 10.1186/s12967-015-0428-x
PMCID: PMC4353456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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