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Article

Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection.

PloS one - 1 Jan 2014

Golden-Mason Lucy, Hahn Young S, Strong Michael, Cheng Linling, Rosen Hugo R

Abstract excerpt

BACKGROUND: Hepatitis C viral (HCV) proteins, including core, demonstrate immuno-modulatory properties; however, the effect of extracellular core on natural killer (NK) cells has not previously been investigated. AIMS: To characterise NKs in acute HCV infection over time, and, to examine the effect of exogenous HCV-core protein on NK cell phenotype and function. METHODS: Acute HCV patients (n = 22), including 10...

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Share to CD56 Antigen
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Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Space

Share to Killer Cells, Natural

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Source

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Identifiers

PMID: 25076408
DOI: 10.1371/journal.pone.0103219
PMCID: PMC4116173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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