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Article

Glycation of Wild-Type Apomyoglobin Induces Formation of Highly Cytotoxic Oligomeric Species.

Journal of cellular physiology - 1 Nov 2015

Iannuzzi Clara, Carafa Vincenzo, Altucci Lucia, Irace Gaetano, Borriello Margherita, Vinciguerra Roberto, Sirangelo Ivana

Abstract excerpt

Protein glycation is a non-enzymatic, irreversible modification of protein amino groups by reactive carbonyl species leading to the formation of advanced glycation end products (AGEs). Several proteins implicated in neurodegenerative diseases have been found to be glycated in vivo and the extent of glycation is related to the pathologies of the patients. Although it is now accepted that there is a direct...

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PMID: 25846844
DOI: 10.1002/jcp.25011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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