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Article

Misfolding and amyloid aggregation of apomyoglobin.

International journal of molecular sciences - 9 Jul 2013

Iannuzzi Clara, Maritato Rosa, Irace Gaetano, Sirangelo Ivana

Abstract excerpt

Apomyoglobin is an excellent example of a monomeric all α-helical globular protein whose folding pathway has been extensively studied and well characterized. Structural perturbation induced by denaturants or high temperature as well as amino acid substitution have been described to induce misfolding and, in some cases, aggregation. In this article, we review the molecular mechanism of the aggregation process...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23839096
DOI: 10.3390/ijms140714287
PMCID: PMC3742244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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