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Article

Association of ABCB1 C3435T polymorphism with phenobarbital resistance in Thai patients with epilepsy.

Journal of clinical pharmacy and therapeutics - 1 Jun 2015

Keangpraphun T, Towanabut S, Chinvarun Y, Kijsanayotin P

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: One-third of patients with epilepsy are resistant to anti-epileptic drugs (AEDs). Drug-resistant epilepsy is believed to be multifactorial involving both genetic and non-genetic factors. Genetic variations in the ABCB1 gene encoding the drug efflux transporter, p-glycoprotein (p-gp), may influence the interindividual variability in AED response by limiting drugs from reaching their...

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Source

Identifiers

PMID: 25846690
DOI: 10.1111/jcpt.12263

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of ABCB1 C3435T polymorphism with phenobarbital resistance in Thai patients with epilepsy.PMID 25846690Read ↗

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