Article
[The effect of central administration of the neurotrophic factors BDNF and GDNF on the functional activity and expression of the serotonin 5-HT2A receptors in mice genetically predisposed to depressive-like behavior].
Molekuliarnaia biologiia - 1 Jan 2000
Tsybko A S, Il'chibaeva T V, Kondaurova E M, Bazovkina D V, Naumenko V S
Abstract excerpt
Brain serotonin (5-HT) system plays an important role in the control of normal and pathological behavior. 5-HT2A receptors are widely implicated in the regulation both normal functions and psychopathologies, especially schizophrenia and depression. Here, we investigated implication of 5-HT2A receptor in mechanisms of neurotrophic factors BDNF and GDNF action. We found that the acute intracerebroventricular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.