Article
Genetic variants reduced POPs-related colorectal cancer risk via altering miRNA binding affinity and m6A modification.
Environment international - 1 Aug 2024
Guo Mengfan, Li Shuwei, Cheng Yifei, Xin Junyi, Zhou Jieyu, Xu Shenya, Ben Shuai, Wang Meilin, Zhang Zhengdong, Gu Dongying
Abstract excerpt
Exposure to persistent organic pollutants (POPs) may contribute to colorectal cancer risk, but the underlying mechanisms of crucial POPs exposure remain unclear. Hence, we systematically investigated the associations among POPs exposure, genetics and epigenetics and their effects on colorectal cancer. A case-control study was conducted in the Chinese population for detecting POPs levels. We measured the...
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