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Article

Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance.

Transplantation - 1 Sept 2015

Lal Girdhari, Nakayama Yumi, Sethi Apoorva, Singh Amit K, Burrell Bryna E, Kulkarni Neeraja, Brinkman C Colin, Iwami Daiki, Zhang Tianshu, Bromberg Jonathan S

Abstract excerpt

BACKGROUND: Blocking CD40-CD40L costimulatory signals induces transplantation tolerance. Although B-cell depletion prevents alloantibody formation, nonhumoral functions of B cells in tolerance have not been well characterized. We investigated whether specific subsets of B cell or B cell-derived i...

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Source

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Identifiers

PMID: 25839706
DOI: 10.1097/TP.0000000000000718
PMCID: PMC4551603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25839706-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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