Article
Regulatory B10 cells display an altered homoeostasis in acute graft-versus-host disease.
European journal of haematology - 1 Feb 2017
Chakupurakal Geothy, Garcia-Marquez María Alejandra, Shimabukuro-Vornhagen Alexander, Kluth Sandra, Schlosser Hans, Theurich Sebastian, Scheid Christof, Hallek Michael, Holtick Udo, von Bergwelt-Baildon Michael
Abstract excerpt
OBJECTIVE: The role of B cells and the subgroup of IL-10 producing B cells, known to have a regulatory function, in patients following a haematopoietic stem cell transplant (alloSCT) has not been clearly understood to date. METHODS: We prospectively recruited 95 patients following an alloSCT and studied the B-cell reconstitution on days 30, 90 and 150. Regulatory B10 cells could be analysed in 22 consecutively...
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