Article
Genetic association between PER3 genetic polymorphisms and cancer susceptibility: a meta-analysis.
Medicine - 1 Apr 2015
Geng Peiliang, Ou Juanjuan, Li Jianjun, Wang Ning, Xie Ganfeng, Sa Rina, Liu Chen, Xiang Lisha, Liang Houjie
Abstract excerpt
The genes along the circadian pathways control and modulate circadian rhythms essential for the maintenance of physiological homeostasis through self-sustained transcription-translation feedback loops. PER3 (period 3) is a circadian pathway gene and its variants (rs1012477, 4/5-repeat) have frequently been associated with human cancer. The mixed findings, however, make the role of the 2 variants in cancer...
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