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Article

Dissecting the genetic architecture of circadian rhythms in human tissues using a quantitative circadian deviation score.

Genome biology - 25 Sept 2025

Li Zheyu, Chen Liang

Abstract excerpt

BACKGROUND: Circadian rhythms influence various physiological and behavioral processes, including sleep, metabolism, and immune response. Although key regulatory factors of biological clocks have been identified and genome-wide association studies have pinpointed some genetic variants linked to sleep traits, the genetic architecture underlying circadian rhythms remains incompletely understood. RESULTS: Here, we...

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Identifiers

PMID: 40999520
DOI: 10.1186/s13059-025-03767-4
PMCID: PMC12462297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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