Article
Circadian gene variants in cancer.
Annals of medicine - 1 Jun 2014
Kettner Nicole M, Katchy Chinenye A, Fu Loning
Abstract excerpt
Humans as diurnal beings are active during the day and rest at night. This daily oscillation of behavior and physiology is driven by an endogenous circadian clock not environmental cues. In modern societies, changes in lifestyle have led to a frequent disruption of the endogenous circadian homeostasis leading to increased risk of various diseases including cancer. The clock is operated by the feedback loops of...
Topics
- Animals
- Circadian Clocks
- Circadian Rhythm
- Genetic Variation
- Homeostasis
- Humans
- Mutation
- Neoplasms
- Risk Factors
