Article
Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.
Cancer research - 15 Dec 2009
Zhu Yong, Stevens Richard G, Hoffman Aaron E, Fitzgerald Liesel M, Kwon Erika M, Ostrander Elaine A, Davis Scott, Zheng Tongzhang, Stanford Janet L
Abstract excerpt
Circadian genes are responsible for maintaining the ancient adaptation of a 24-hour circadian rhythm and influence a variety of cancer-related biological pathways, including the regulation of sex hormone levels. However, few studies have been undertaken to investigate the role of circadian genes...
Topics
- Adult
- Aged
- Case-Control Studies
- Circadian Rhythm
- Genetic Predisposition to Disease
- Genetic Variation
- Genotype
- Haplotypes
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Prostate-Specific Antigen
- Prostatic Neoplasms