Article
Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.
Cancer research - 15 Dec 2009
Zhu Yong, Stevens Richard G, Hoffman Aaron E, Fitzgerald Liesel M, Kwon Erika M, Ostrander Elaine A, Davis Scott, Zheng Tongzhang, Stanford Janet L
Abstract excerpt
Circadian genes are responsible for maintaining the ancient adaptation of a 24-hour circadian rhythm and influence a variety of cancer-related biological pathways, including the regulation of sex hormone levels. However, few studies have been undertaken to investigate the role of circadian genes in the development of prostate cancer, the most common cancer type among men (excluding nonmelanoma skin cancer). The...
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