Article
LPIN1 rs13412852 polymorphism in pediatric nonalcoholic fatty liver disease.
Journal of pediatric gastroenterology and nutrition - 1 May 2012
Valenti Luca, Motta Benedetta Maria, Alisi Anna, Sartorelli Rita, Buonaiuto Giulia, Dongiovanni Paola, Rametta Raffaela, Pelusi Serena, Fargion Silvia, Nobili Valerio
Abstract excerpt
OBJECTIVES: The aim of the present study was to evaluate whether the lipin1 rs13412852 C>T polymorphism is associated with nonalcoholic steatohepatitis and fibrosis in pediatric Italian patients with nonalcoholic fatty liver disease (NAFLD). METHODS: A total of 142 untreated, consecutive children and 115 adults with biopsy-proven NAFLD and 337 healthy controls without steatosis were studied. Liver histology was...
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