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Article

Genetic polymorphisms in non-alcoholic fatty liver disease in obese Egyptian children

1 Jan 2011

Abstract excerpt

BACKGROUND/AIM: Polymorphisms in the promoter of microsomal triglyceride transfer protein (MTP) lead to decreased MTP transcription, less export of triglyceride from hepatocytes, and greater intracellular triglyceride accumulation. Therefore, functional polymorphisms in MTP may be involved in determining susceptibility to nonalcoholic steatohepatitis (NASH). The aim of this study is to examine the effect of some...

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PMID: 21727734
DOI: 10.4103/1319-3767.82582

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