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Article

Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 2015

Jakovcevski Mira, Ruan Hongyu, Shen Erica Y, Dincer Aslihan, Javidfar Behnam, Ma Qi, Peter Cyril J, Cheung Iris, Mitchell Amanda C, Jiang Yan, Lin Cong L, Pothula Venu, Stewart A Francis, Ernst Patricia, Yao Wei-Dong, Akbarian Schahram

Abstract excerpt

Neuronal histone H3-lysine 4 methylation landscapes are defined by sharp peaks at gene promoters and other cis-regulatory sequences, but molecular and cellular phenotypes after neuron-specific deletion of H3K4 methyl-regulators remain largely unexplored. We report that neuronal ablation of the H3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25834037
DOI: 10.1523/JNEUROSCI.3004-14.2015
PMCID: PMC4380991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25834037-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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