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Article

The maternal-age-associated risk of congenital heart disease is modifiable.

Nature - 9 Apr 2015

Schulkey Claire E, Regmi Suk D, Magnan Rachel A, Danzo Megan T, Luther Herman, Hutchinson Alayna K, Panzer Adam A, Grady Mary M, Wilson David B, Jay Patrick Y

Abstract excerpt

Maternal age is a risk factor for congenital heart disease even in the absence of any chromosomal abnormality in the newborn. Whether the basis of this risk resides with the mother or oocyte is unknown. The impact of maternal age on congenital heart disease can be modelled in mouse pups that harb...

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Identifiers

PMID: 25830876
DOI: 10.1038/nature14361
PMCID: PMC4393370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25830876-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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