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Article

αII-spectrin regulates invadosome stability and extracellular matrix degradation.

PloS one - 1 Jan 2015

Ponceau Aurélie, Albigès-Rizo Corinne, Colin-Aronovicz Yves, Destaing Olivier, Lecomte Marie Christine

Abstract excerpt

Invadosomes are actin-rich adhesion structures involved in tissue invasion and extracellular matrix (ECM) remodelling. αII-Spectrin, an ubiquitous scaffolding component of the membrane skeleton and a partner of actin regulators (ABI1, VASP and WASL), accumulates highly and specifically in the invadosomes of multiple cell types, such as mouse embryonic fibroblasts (MEFs) expressing SrcY527F, the constitutively...

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Source

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Identifiers

PMID: 25830635
DOI: 10.1371/journal.pone.0120781
PMCID: PMC4382279

Genes

ABI1
VASP
WASL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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