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Article

βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases

6 Nov 2020

Abstract excerpt

βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton protein present in all nucleated cells. Interestingly, βII spectrin is essential for the development of various organs such as nerve, epithelium, inner ear, liver and heart. The functions of βII spectrin include not only establishing and maintaining the cell structure but also regulating a variety of cellular functions, such as...

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PMID: 33390831
DOI: 10.7150/ijbs.52375

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