Article
Organizing the fluid membrane bilayer: diseases linked to spectrin and ankyrin.
Trends in molecular medicine - 1 Jan 2008
Bennett Vann, Healy Jane
Abstract excerpt
Ankyrin and spectrin were first discovered as binding partners in the membrane skeleton of human erythrocytes. Mutations in genes encoding these proteins cause hereditary spherocytosis. Recent advances reveal that ankyrin and spectrin are required for organization of a surprisingly diverse set of proteins, including ion channels and cell adhesion molecules that are localized in specialized membrane domains in...
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