Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasion

5 Feb 2014

Abstract excerpt

Acquisition of an invasive phenotype is prerequisite for tumor metastasis. Degradation of the extracellular matrix (ECM), and subsequent invasion by tumor cells, is mediated, in part, through subcellular structures called invadopodia. Src-dependent cytoskeletal rearrangements are required to form invadopodia, and here we identify an association between Src, epidermal growth factor receptor (EGFR), and β1 integrin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24496451
DOI: 10.1242/jcs.134734

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasionPMID 24496451Read ↗

Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturationSemantic proximity Read ↗

Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cellsSemantic proximity Read ↗

Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation.Semantic proximity Read ↗

SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPasesSemantic proximity Read ↗

The emerging role of class-3 semaphorins and their neuropilin receptors in oncologySemantic proximity Read ↗

Integrin traffic – the updateSemantic proximity Read ↗

Intracellular nanovesicles mediate integrin trafficking during cell migrationSemantic proximity Read ↗

αII-spectrin regulates invadosome stability and extracellular matrix degradation.Semantic proximity Read ↗

Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells.Semantic proximity Read ↗

FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation.Semantic proximity Read ↗

Cortactin promotes exosome secretion by controlling branched actin dynamics.Semantic proximity Read ↗

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.