Article
Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES).
PloS one - 1 Jan 2015
Winnier Deidre A, Fourcaudot Marcel, Norton Luke, Abdul-Ghani Muhammad A, Hu Shirley L, Farook Vidya S, Coletta Dawn K, Kumar Satish, Puppala Sobha, Chittoor Geetha, Dyer Thomas D, Arya Rector, Carless Melanie, Lehman Donna M, Curran Joanne E, Cromack Douglas T, Tripathy Devjit, Blangero John, Duggirala Ravindranath, Göring Harald H H, DeFronzo Ralph A, Jenkinson Christopher P
Abstract excerpt
Type 2 diabetes (T2D) is a complex metabolic disease that is more prevalent in ethnic groups such as Mexican Americans, and is strongly associated with the risk factors obesity and insulin resistance. The goal of this study was to perform whole genome gene expression profiling in adipose tissue t...
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