Article
Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families.
Clinical epigenetics - 1 Jan 2016
Mamtani Manju, Kulkarni Hemant, Dyer Thomas D, Göring Harald H H, Neary Jennifer L, Cole Shelley A, Kent Jack W, Kumar Satish, Glahn David C, Mahaney Michael C, Comuzzie Anthony G, Almasy Laura, Curran Joanne E, Duggirala Ravindranath, Blangero John, Carless Melanie A
Abstract excerpt
BACKGROUND: There is growing interest in the hypertriglyceridemic waist (HTGW) phenotype, defined as high waist circumference (≥95 cm in males and ≥80 cm in females) combined with high serum triglyceride concentration (≥2.0 mmol/L in males and ≥1.5 mmol/L in females) as a marker of type 2 diabetes (T2D) and cardiovascular disease. However, the prevalence of this phenotype in high-risk populations, its association...
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